Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31104494 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBCNR2KDM5B | |
| SCHEMBL31104496 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBCNR2KDM5B | |
| SCHEMBL31104090 | 0.84 | SLC6A3 (0.39) | ALDH1A1LMNAPOLBCNR2KDM5B | |
| SCHEMBL25342197 | 0.80 | RXRA (0.41) | ALDH1A1LMNAPOLBCNR2CYP4F2 | |
| SCHEMBL31104446 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAPOLBCNR2CYP4F2 | |
| SCHEMBL31386712 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAPOLBCNR2KDM5B | |
| SCHEMBL31104264 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAPOLBCNR2CYP4F2 | |
| SCHEMBL31103775 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBCNR2CYP4F2 | |
| SCHEMBL31104026 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBCNR2CYP4F2 | |
| SCHEMBL31103927 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAPOLBCNR2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022001767-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | 武汉朗来科技发展有限公司 | 2022-01-06 | — | — | WO | disclosed |