Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23795368 | 1.00 | MMP13 (0.41) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL24177978 | 0.88 | CNR1 (0.44) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL30439348 | 0.88 | CNR1 (0.44) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL23795306 | 0.88 | CNR1 (0.44) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL23795379 | 0.83 | HTR6 (0.39) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL24177901 | 0.83 | HTR6 (0.39) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL23810437 | 0.80 | MMP13 (0.45) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL23795420 | 0.80 | MMP13 (0.45) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL30439444 | 0.80 | MMP13 (0.43) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL23795385 | 0.78 | MMP13 (0.41) | MMP13MMP1MMP9HTR6ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002265-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | BEIJING INCREASE INNOVATIVE DRUG CO., LTD (CN) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002265-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | ROCK1, RHOA, ROCK2 | MMP13 269/4885MMP1 218/4885MMP9 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.