Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 9/20 | 0.56 |
| ▸ | INSR | P06213 | 6/20 | 0.56 |
| ▸ | IGF1R | P08069 | 6/20 | 0.56 |
| ▸ | EGFR | P00533 | 10/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25450645 | 0.91 | INSR (0.59) | ALKINSRIGF1REGFRPLK1 | |
| SCHEMBL24179052 | 0.89 | INSR (0.69) | ALKINSRIGF1REGFRPLK1 | |
| SCHEMBL30216900 | 0.89 | EGFR (0.67) | ALKINSRIGF1REGFR | |
| SCHEMBL25449097 | 0.89 | EGFR (0.67) | ALKINSRIGF1REGFR | |
| SCHEMBL25449156 | 0.88 | PLK1 (0.54) | ALKEGFRPLK1 | |
| SCHEMBL24178907 | 0.88 | ALK (0.69) | ALKINSRIGF1REGFRPLK1 | |
| SCHEMBL24178982 | 0.86 | EGFR (0.57) | ALKINSRIGF1REGFR | |
| SCHEMBL25450025 | 0.84 | EGFR (0.60) | ALKINSRIGF1REGFRPLK1 | |
| SCHEMBL24179127 | 0.84 | EGFR (0.66) | ALKINSRIGF1REGFR | |
| SCHEMBL24179047 | 0.83 | EGFR (0.65) | ALKINSRIGF1REGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4177258-A1 | ARYLPHOSPHINE OXIDE COMPOUNDS AND USE THEREOF | Chengdu Di'Ao Jiuhong Pharmaceutical Factory (CN) | 2023-05-10 | — | — | EP | disclosed |
| WO-2022002241-A1 | ARYLPHOSPHINE OXIDE COMPOUNDS AND USE THEREOF | 成都地奥九泓制药厂 | 2022-01-06 | — | — | WO | disclosed |