Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.52 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.52 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.52 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25868917 | 0.84 | POLB (0.59) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL25834953 | 0.84 | POLB (0.59) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7295274 | 0.84 | RAB9A (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL26998004 | 0.84 | POLB (0.59) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17335855 | 0.82 | HPGD (0.73) | POLBKMT2AHPGDLMNASMN1; SMN2 | |
| SCHEMBL17117413 | 0.82 | PLAAT3 (0.68) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17077863 | 0.81 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL25594203 | 0.80 | RAB9A (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL15679869 | 0.79 | PLAAT3 (0.73) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10408493 | 0.79 | KMT2A (0.61) | HDAC2HDAC8POLBKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220523-B2 | Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein | UNIVERSITÄT BASEL (CH) | 2022-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220523-B2 | Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein | MAG, PMP22, SIGLEC7 | HDAC3 1773/4885HDAC1 858/4885HDAC2 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.