Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.56 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.56 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.56 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26739831 | 0.90 | LMNA (0.65) | RAB9AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL17117413 | 0.88 | PLAAT3 (0.68) | RAB9AHPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL7280705 | 0.85 | HDAC3 (0.77) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL24179797 | 0.84 | HDAC3 (0.63) | RAB9APOLBKMT2AHPGDHDAC3 | |
| SCHEMBL26998004 | 0.84 | POLB (0.59) | RAB9APOLBKMT2AHPGDHDAC3 | |
| SCHEMBL25868917 | 0.84 | POLB (0.59) | RAB9APOLBKMT2AHPGDHDAC3 | |
| SCHEMBL25834953 | 0.84 | POLB (0.59) | RAB9APOLBKMT2AHPGDHDAC3 | |
| SCHEMBL7436977 | 0.84 | HDAC3 (0.79) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7441298 | 0.84 | HDAC3 (0.79) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7441870 | 0.84 | HDAC3 (0.79) | KMT2AHDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223598-B1 | CATECHOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FISONS plc (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4939147-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC. (GB) | 1990-07-03 | — | — | US | disclosed |
| US-4922022-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| US-4883804-A | Aromatic compounds | FISONS PLC (GB) | 1989-11-28 | — | — | US | disclosed |
| EP-0223598-A2 | Catecholamine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-05-27 | — | — | EP | disclosed |