SCHEMBL557152

SCHEMBL557152

COc1ccc(C(=O)C(=O)c2ccc(OC)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 1.00
CES1 P23141 2/20 1.00
MAPT P10636 2/20 0.72
CA1 P00915 6/20 0.70
CA2 P00918 6/20 0.70
PARP10 Q53GL7 2/20 0.67
PARP1 P09874 1/20 0.67
PARP2 Q9UGN5 1/20 0.67
PARP4 Q9UKK3 1/20 0.67
PLK1 P53350 1/20 0.61
GSK3B P49841 1/20 0.59
MEN1 O00255 1/20 0.59
LMNA P02545 1/20 0.59
MAPK1 P28482 1/20 0.59
RAB9A P51151 1/20 0.59
KMT2A Q03164 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
HDAC3 O15379 1/20 0.59
HDAC4 P56524 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14507040 1.00 CES2 (1.00) CES2CES1MAPTCA1CA2
SCHEMBL29548151 0.97 CES2 (0.95) CES2CES1MAPTCA1CA2
SCHEMBL8669380 0.93 CES2 (0.86) CES2CES1MAPTCA1CA2
SCHEMBL14947045 0.91 CES2 (0.83) CES2CES1MAPTCA1CA2
SCHEMBL12700321 0.91 CES2 (0.83) CES2CES1MAPTCA1CA2
SCHEMBL2156563 0.91 CES2 (1.00) CES2CES1MAPTCA1CA2
Bromide SCHEMBL981452 0.89 CES2 (0.96) CES2CES1MAPTCA1CA2
SCHEMBL9125486 0.89 CES2 (0.79) CES2CES1MAPTCA1CA2
Hydrochloric Acid SCHEMBL905770 0.89 CES2 (0.96) CES2CES1MAPTCA1CA2
SCHEMBL2320546 0.88 CES2 (0.78) CES2CES1MAPTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 774 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250000813-A1 OROMUCOSAL NANOFIBER CARRIERS FOR THERAPEUTIC TREATMENT INSTAR TECHNOLOGIES A.S. (CZ) 2025-01-02 US claimed
US-12180183-B2 Water-soluble fluorescent probe and nanoparticals with aggregation-induced emission effect for ovarian cancer and preparation method and use thereof HUNAN TARGETING DETECTION TECHNOLOGY CO., LTD. (CN) 2024-12-31 US claimed
CN-119143591-A Benzyl benzoyl or fluoro alkane substituted phenol compound and synthetic method and application thereof 河北中医药大学 2024-12-17 CN claimed
US-12012385-B1 4,5-bis(4-methoxyphenyl)-1-hexyl-2-phenyl-1H-imidazole as an antimicrobial compound King Faisal University (SA) 2024-06-18 US claimed
US-20240168374-A1 PHOTORESIST COMPOSITION TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2024-05-23 US claimed
US-11964946-B1 4,5-bis(4-methoxyphenyl)-1-hexyl-2-(4-nitrophenyl)-1H-imidazole as an antimicrobial compound King Faisal University (SA) 2024-04-23 US claimed
EP-3976878-B1 METHODS OF MAKING A DEFLECTION MEMBER PROCTER & GAMBLE (US) 2023-07-05 EP claimed
US-11590694-B2 Methods of making a deflection member THE PROCTER & GAMBLE COMPANY (US) 2023-02-28 US claimed
EP-3976878-A1 METHODS OF MAKING A DEFLECTION MEMBER The Procter & Gamble Company (US) 2022-04-06 EP claimed
US-8993650-B2 Mixable and color tone freely reproducible dental coloring material composition, and set and method thereof KABUSHIKI KAISHA SHOFU (JP) 2015-03-31 US claimed
US-7973034-B2 Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2011-07-05 US claimed
US-6328793-B1 FOR USE IN INK JET PRINTING PROCESSES, INCLUDING PIEZOELECTRIC INK JET PRINTING, ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-12-11 US claimed
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US claimed
EP-0043480-B1 PROCESS FOR FORMING METALLIC IMAGES Hitachi, Ltd. (JP) 1985-04-03 EP claimed
US-4347304-A PHOTOSENSITIZATION WITH DISILANES OR ORGANIC COMPOUNDS HAVING COUPLED GERMANIUM OR TIN MOLECULES; PHOTORESISTS; POSITIVES; PLATING HITACHI, LTD. (JP) 1982-08-31 US claimed
EP-0043480-A2 Process for forming metallic images Hitachi, Ltd. (JP) 1982-01-13 EP claimed
US-4087463-A COBALT CARBONYL CATALYST MONSANTO COMPANY (US) 1978-05-02 US claimed
JP-4244923-A None JP disclosed
US-3948894-A ANTIINFLAMMATORY ELI LILLY AND COMPANY (US) 1976-04-06 US disclosed
US-3941811-A Oxidation process ROUSSEL-UCLAF (FR) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12180183-B2 Water-soluble fluorescent probe and nanoparticals with aggregation-induced emission effect for ovarian cancer and preparation method and use thereof PHOSPHO1, LPAR1, LPAR3 CES2 4835/4885CES1 3127/4885MAPT 2541/4885
US-12012385-B1 4,5-bis(4-methoxyphenyl)-1-hexyl-2-phenyl-1H-imidazole as an antimicrobial compound TLR4, CASP4, IL4 CES2 3711/4885CES1 3926/4885MAPT 1865/4885
US-11964946-B1 4,5-bis(4-methoxyphenyl)-1-hexyl-2-(4-nitrophenyl)-1H-imidazole as an antimicrobial compound TLR4, CASP4, IL4 CES2 3587/4885CES1 3617/4885MAPT 2407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.