Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.60 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.60 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.60 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.60 |
| ▸ | TOP1 | P11387 | 3/20 | 0.60 |
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25C | P30307 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30574283 | 0.85 | TOP1 (0.66) | POLMPOLKPOLLPOLHTOP1 | |
| SCHEMBL24194098 | 0.85 | TOP1 (0.66) | POLMPOLKPOLLPOLHTOP1 | |
| SCHEMBL16076555 | 0.81 | KCNA3 (0.62) | ELANECYP1A2CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL9017760 | 0.80 | ELANE (0.67) | ELANECYP1A2CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL21076346 | 0.79 | ALDH1A1 (0.64) | POLMPOLKPOLLPOLHCDC25B | |
| SCHEMBL28986871 | 0.77 | KCNA3 (0.70) | ELANECYP1A2CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL21543711 | 0.77 | CYP1A2 (0.49) | ELANECYP1A2CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL9711411 | 0.77 | TOP1 (0.51) | POLMPOLKPOLLPOLHTOP1 | |
| SCHEMBL3414850 | 0.75 | TOP1 (1.00) | POLMPOLKPOLLPOLHTOP1 | |
| SCHEMBL30003440 | 0.75 | TOP1 (1.00) | POLMPOLKPOLLPOLHTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113368087-A | Juglone derivatives and application thereof in preparation of drugs for treating brain tumors through chemotherapy | 复旦大学附属华山医院 | 2021-09-10 | — | — | CN | claimed |
| US-20220011488-A1 | COMPOUND, POLYMERIZABLE COMPOSITION, CURED PRODUCT, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2022-01-13 | — | — | US | disclosed |
| CN-113368087-A | Juglone derivatives and application thereof in preparation of drugs for treating brain tumors through chemotherapy | 复旦大学附属华山医院 | 2021-09-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220011488-A1 | COMPOUND, POLYMERIZABLE COMPOSITION, CURED PRODUCT, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | PDAP1, PHOSPHO1, DAD1 | POLM 2824/4885POLK 3298/4885POLL 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.