Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21543826 | 0.95 | KCNA3 (0.46) | CYP1A2CYP2C9CYP2C19CYP19A1ELANE | |
| SCHEMBL21543827 | 0.92 | CYP2A6 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1ELANE | |
| SCHEMBL21543800 | 0.85 | TTR (0.46) | TDP1CYP2A6ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL19735979 | 0.84 | ELANE (0.44) | CYP1A2CYP2C9CYP2C19CYP19A1ELANE | |
| SCHEMBL11436177 | 0.83 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19CYP19A1ELANE | |
| SCHEMBL11365580 | 0.83 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19CYP19A1ELANE | |
| SCHEMBL16076555 | 0.81 | KCNA3 (0.62) | CYP1A2CYP2C9CYP2C19CYP19A1ELANE | |
| SCHEMBL29129708 | 0.81 | KCNA3 (0.44) | CYP1A2CYP2C9CYP2C19CYP19A1KCNA3 | |
| SCHEMBL30930077 | 0.81 | ALOX15 (0.43) | CYP1A2CYP2C19KCNA3TDP1ALDH1A1 | |
| SCHEMBL9017760 | 0.80 | ELANE (0.67) | CYP1A2CYP2C9CYP2C19CYP19A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-06-01 | — | — | US | disclosed |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021455-B2 | Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient | TAS2R20, BLVRB, FDPS | CYP1A2 2233/4885CYP2C9 800/4885CYP2C19 609/4885 |
| US-20190345126-A1 | NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | TAS2R20, BLVRB, NOTUM | CYP1A2 2381/4885CYP2C9 854/4885CYP2C19 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.