Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196174 | 0.83 | MAP2 (0.43) | KEAP1NFE2L2MAP2BRD3CFD | |
| SCHEMBL2730323 | 0.82 | ALDH1A1 (0.59) | CNR1KEAP1NFE2L2MAP2CFD | |
| SCHEMBL24196832 | 0.81 | MAP2 (0.41) | KEAP1NFE2L2MAP2BRD3CFD | |
| SCHEMBL24196991 | 0.79 | CNR1 (0.52) | CNR1KEAP1NFE2L2MAP2ALDH1A1 | |
| SCHEMBL2730512 | 0.79 | MAP2 (0.61) | CNR1KEAP1NFE2L2MAP2ALDH1A1 | |
| SCHEMBL24196180 | 0.75 | GABRA1 (0.56) | CNR1KEAP1NFE2L2MAP2ALDH1A1 | |
| SCHEMBL24196942 | 0.75 | PTGS2 (0.59) | CNR1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL3283431 | 0.74 | ALDH1A1 (0.69) | CNR1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL24196994 | 0.73 | CNR1 (0.47) | CNR1KEAP1NFE2L2MAP2ALDH1A1 | |
| SCHEMBL24196586 | 0.72 | GABRA1 (0.50) | CNR1KEAP1NFE2L2MAP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |