Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 10/20 | 0.40 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | LGMN | Q99538 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196343 | 1.00 | FFAR2 (0.40) | FFAR2GPER1PDE3BPDE3ALRRK2 | |
| SCHEMBL12813284 | 0.87 | LGMN (0.44) | FFAR2LRRK2LGMNPRKDCPIK3CA | |
| SCHEMBL26633120 | 0.83 | PDE3B (0.40) | FFAR2GPER1PDE3BPDE3ALRRK2 | |
| SCHEMBL30403514 | 0.83 | PDE3B (0.40) | FFAR2GPER1PDE3BPDE3ALRRK2 | |
| SCHEMBL29049683 | 0.83 | DRD3 (0.44) | FFAR2GPER1PDE3BPDE3ALRRK2 | |
| SCHEMBL30402974 | 0.81 | GPER1 (0.39) | FFAR2GPER1PDE3BPDE3ALRRK2 | |
| SCHEMBL26633127 | 0.81 | GLRA1 (0.42) | FFAR2GPER1PDE3BPDE3ALRRK2 | |
| SCHEMBL29049699 | 0.81 | GLRA1 (0.42) | FFAR2GPER1PDE3BPDE3ALRRK2 | |
| SCHEMBL24196403 | 0.80 | ADORA2A (0.44) | LRRK2LGMNPIK3CAMTOR | |
| SCHEMBL24196407 | 0.80 | ADORA2A (0.44) | LRRK2LGMNPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |