Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23205926 | 0.81 | DRD3 (0.39) | SCN9ASCN10APARP1CA12CA1 | |
| SCHEMBL10120657 | 0.78 | SCN9A (0.40) | SCN9ASCN10APARP1CA12CA1 | |
| SCHEMBL12362752 | 0.77 | DRD3 (0.39) | SCN9ASCN10APARP1CA12CA1 | |
| SCHEMBL10105625 | 0.74 | DRD3 (0.39) | SCN9ASCN10APARP1CA12CA1 | |
| SCHEMBL12427181 | 0.74 | RAB9A (0.56) | SCN9ASCN10ACA12CA1CA2 | |
| SCHEMBL12436076 | 0.74 | DRD2 (0.43) | RAB9AMEN1NPC1KMT2ADRD2 | |
| SCHEMBL12362751 | 0.73 | DRD3 (0.41) | SCN9ASCN10APARP1CA12CA1 | |
| SCHEMBL2999231 | 0.72 | DRD3 (0.38) | CA12CA1CA2CA4CA6 | |
| SCHEMBL3577171 | 0.72 | MAPT (0.47) | RAB9AMEN1NPC1KMT2ADRD2 | |
| SCHEMBL11659873 | 0.70 | DRD2 (0.54) | SCN9ARAB9AMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |