SCHEMBL2999231

SCHEMBL2999231

CN1CCCN(c2ccc(N)c(F)c2)C1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 5/20 0.38
DRD2 P14416 4/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
F10 P00742 3/20 0.35
F2 P00734 1/20 0.35
PRSS1 P07477 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA5B Q9Y2D0 2/20 0.34
BPTF Q12830 1/20 0.34
BRD4 O60885 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23205926 0.91 DRD3 (0.39) DRD3DRD2ALDH1A1CA12CA1
SCHEMBL24196254 0.79 ATM (0.43) ALDH1A1MAPT
SCHEMBL4711615 0.77 MAPT (0.44) DRD3DRD2SLC6A2SLC6A4F10
SCHEMBL3551615 0.76 ALDH1A1 (0.50) ALDH1A1KDM4EGAA
SCHEMBL10120657 0.75 SCN9A (0.40) DRD3DRD2ALDH1A1CA12CA1
SCHEMBL77996 0.75 BRD9 (0.47) F10ALDH1A1GAA
SCHEMBL24196411 0.75 RAB9A (0.46) DRD3DRD2KCNH2
SCHEMBL12362752 0.74 DRD3 (0.39) DRD3DRD2CA12CA1CA2
SCHEMBL5421060 0.74 BRD9 (0.46) F10ALDH1A1GAAMAPTMAPK1
SCHEMBL29348778 0.74 DRD2 (0.53) DRD3DRD2F2ALDH1A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100184767-A1 SUBSTITUTED OXAZOLIDINONES AND USE THEREOF ROHRIG SUSANNE 2010-07-22 US disclosed
US-20100184767-A1 SUBSTITUTED OXAZOLIDINONES AND USE THEREOF ROHRIG SUSANNE 2010-07-22 US disclosed
US-20100184767-A1 SUBSTITUTED OXAZOLIDINONES AND USE THEREOF ROHRIG SUSANNE 2010-07-22 US disclosed
WO-2008155034-A1 SUBSTITUTED OXAZOLIDINONES AND THE USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184767-A1 SUBSTITUTED OXAZOLIDINONES AND USE THEREOF XDH, OXA1L, PPOX DRD3 1778/4885DRD2 2776/4885SLC6A2 4063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.