Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468657 | 0.85 | TAAR1 (0.55) | ALDH1A1TDP1TAAR1HDAC2LPL | |
| SCHEMBL15519549 | 0.82 | TAAR1 (0.61) | ALDH1A1TDP1TAAR1HDAC2LPL | |
| SCHEMBL3717306 | 0.82 | TDP2 (0.51) | ALDH1A1TAAR1LPLLIPGPRMT6 | |
| SCHEMBL11936142 | 0.81 | PRMT6 (0.45) | ALDH1A1CYP3A4TSHRTDP1TAAR1 | |
| SCHEMBL31201086 | 0.79 | FLT3 (0.48) | TAAR1LPLLIPGPRMT6ERN1 | |
| SCHEMBL20462888 | 0.78 | ERN1 (0.46) | TAAR1LPLLIPGPRMT6ERN1 | |
| SCHEMBL29208883 | 0.78 | ERN1 (0.58) | CYP3A4TDP1TAAR1PRMT6ERN1 | |
| SCHEMBL26673582 | 0.77 | TAAR1 (0.54) | TAAR1HDAC2LPLLIPGPRMT6 | |
| SCHEMBL19354601 | 0.76 | TAAR1 (0.44) | ALDH1A1TSHRTAAR1LPLLIPG | |
| SCHEMBL13105784 | 0.75 | PRMT6 (0.47) | ALDH1A1TSHRTDP1TAAR1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011211-A1 | DEOXYNOJIRIMYCIN DERIVATIVES AS GLUCOSIDASE INHIBITORS | EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. (US) | 2022-01-13 | — | — | WO | disclosed |