Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18404400 | 0.91 | LTA4H (0.44) | GBA1CCR3ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL12900566 | 0.89 | LTA4H (0.46) | GBA1CCR3SLC6A4SLC6A3 | |
| SCHEMBL7446113 | 0.75 | MEN1 (0.49) | GBA1ALDH1A1 | |
| SCHEMBL14734507 | 0.75 | GRIN2B (0.49) | GRIN2B | |
| SCHEMBL16902819 | 0.75 | GRIN2B (0.49) | GRIN2B | |
| SCHEMBL3634313 | 0.75 | EPHX2 (0.48) | GBA1GRIN2B | |
| SCHEMBL1119559 | 0.75 | GBA1 (0.43) | GBA1CCR3ALDH1A1 | |
| SCHEMBL12527362 | 0.75 | GBA1 (0.43) | GBA1CCR3ALDH1A1MGLL | |
| SCHEMBL1119467 | 0.75 | ALDH1A1 (0.59) | GBA1CCR3ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL31276928 | 0.75 | GBA1 (0.43) | GBA1CCR3ALDH1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |