Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20972406 | 0.88 | HTT (0.38) | SIGMAR1HTTL3MBTL1GAAMAPT | |
| SCHEMBL21386084 | 0.83 | KCNN4 (0.40) | SIGMAR1KCNN4LMNATP53CES2 | |
| SCHEMBL24196886 | 0.82 | MAPT (0.35) | KMT2ALMNAL3MBTL1MAPTCA12 | |
| SCHEMBL24196887 | 0.80 | CA2 (0.34) | KMT2ALMNAL3MBTL1GAAMAPT | |
| SCHEMBL1846699 | 0.79 | ALDH1A1 (0.32) | MAPT | |
| SCHEMBL24196884 | 0.78 | HDAC3 (0.41) | KMT2ALMNAL3MBTL1GAAALOX12 | |
| SCHEMBL24196900 | 0.77 | HDAC1 (0.37) | KMT2ALMNAHTTL3MBTL1MAPT | |
| SCHEMBL24196866 | 0.76 | MEN1 (0.43) | KMT2ALMNAHTTTAAR1 | |
| SCHEMBL10475185 | 0.75 | TSHR (0.38) | KCNN4LMNAL3MBTL1MAPTALOX12 | |
| SCHEMBL8090427 | 0.75 | TSHR (0.38) | KCNN4LMNAL3MBTL1MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |
| CN-103183624-B | Catalyst used for olefine polymerization or copolymerization and preparation method thereof | 中国科学院上海有机化学研究所 | 2017-04-19 | — | — | CN | disclosed |
| CN-103183624-A | Catalyst used for olefine polymerization or copolymerization and preparation method thereof | SHANGHAI INST ORGANIC CHEM | 2013-07-03 | — | — | CN | disclosed |