Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28446477 | 0.89 | HPGD (0.40) | MAPTALDH1A1TDP1LMNAALB | |
| SCHEMBL19362577 | 0.85 | L3MBTL1 (0.45) | ALDH1A1TDP1LMNAALBCYP2C9 | |
| SCHEMBL8240628 | 0.82 | MMP13 (0.36) | MAPTALDH1A1TDP1ACHELMNA | |
| SCHEMBL24196887 | 0.82 | CA2 (0.34) | MAPTALDH1A1TDP1LMNACYP2C9 | |
| SCHEMBL24196865 | 0.82 | SIGMAR1 (0.36) | MAPTLMNACA12CA9L3MBTL1 | |
| SCHEMBL13985325 | 0.79 | KAT2B (0.38) | MAPTALDH1A1 | |
| SCHEMBL24196900 | 0.79 | HDAC1 (0.37) | MAPTALDH1A1LMNATSHRCA2 | |
| SCHEMBL24196866 | 0.78 | MEN1 (0.43) | ALDH1A1LMNACA2MEN1KMT2A | |
| SCHEMBL12180351 | 0.76 | ACHE (0.40) | MAPTALDH1A1TDP1ACHELMNA | |
| SCHEMBL24196873 | 0.75 | ALDH1A1 (0.36) | MAPTALDH1A1LMNACYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |