SCHEMBL3564528

SCHEMBL3564528

[O-][S+](Cc1cccc(Cl)c1)Cc1cccc(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.54
TAAR1 Q96RJ0 3/20 0.50
CYP3A4 P08684 2/20 0.48
IDO1 P14902 2/20 0.48
AGXT P21549 2/20 0.48
HTR3E A5X5Y0 3/20 0.47
HTR3B O95264 3/20 0.47
HTR3A P46098 3/20 0.47
HTR3D Q70Z44 3/20 0.47
HTR3C Q8WXA8 3/20 0.47
CHRM2 P08172 2/20 0.44
SIGMAR1 Q99720 1/20 0.44
AOC3 Q16853 1/20 0.43
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
C3AR1 Q16581 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30837416 1.00 PNMT (0.54) PNMTTAAR1CYP3A4IDO1AGXT
SCHEMBL7810238 0.85 PNMT (0.52) PNMTTAAR1CYP3A4IDO1AGXT
SCHEMBL10381187 0.83 PNMT (0.50) PNMTTAAR1CYP3A4IDO1AGXT
SCHEMBL30837419 0.74 TAAR1 (0.50) TAAR1IDO1AGXT
SCHEMBL3570833 0.74 TAAR1 (0.50) TAAR1IDO1
SCHEMBL776359 0.74 TAAR1 (0.50) TAAR1IDO1AGXT
SCHEMBL30837414 0.74 TAAR1 (0.50) TAAR1IDO1AGXT
SCHEMBL3565658 0.74 TAAR1 (0.50) TAAR1IDO1AGXT
SCHEMBL24196899 0.74 TAAR1 (0.46) PNMTTAAR1CYP3A4IDO1AGXT
SCHEMBL12050856 0.74 TAAR1 (0.74) PNMTTAAR1CYP3A4IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117778339-A Sulfoxide reductase mutant and application thereof in preparation of chiral sulfoxide and sulfinyl ester 遵义医科大学 2024-03-29 CN disclosed
CN-117757763-A Sulfoxide reductase mutant and application thereof in chiral sulfoxide preparation 遵义医科大学 2024-03-26 CN disclosed
US-7776582-B2 for gas chromatography; identifying an optically enhanced chiral ionic liquid (OCIL) for enantiomeric resolution SIGMA-ALDRICH CO. (US) 2010-08-17 US disclosed
US-20090145197-A1 Optically Enhanced Chiral Ionic Liquids SIGMA-ALDRICH CO. NEWCO INC. 2009-06-11 US disclosed
US-20060014955-A1 Optically enhanced chiral ionic liquids ADVANCED SEPARATION TECHNOLOGIES INC. (US) 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014955-A1 Optically enhanced chiral ionic liquids GCG, INF2, ELOVL3 PNMT 2412/4885TAAR1 1789/4885CYP3A4 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.