Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.40 |
| ▸ | PI4KA | P42356 | 3/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24197145 | 0.76 | YTHDC1 (0.56) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24197040 | 0.73 | YTHDC1 (0.59) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24197135 | 0.72 | YTHDC1 (0.64) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24196378 | 0.71 | YTHDC1 (1.00) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24197229 | 0.68 | YTHDC1 (0.55) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24197147 | 0.68 | YTHDC1 (0.55) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24197146 | 0.68 | YTHDC1 (0.55) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24197042 | 0.67 | YTHDC1 (0.53) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24708227 | 0.66 | YTHDC1 (0.88) | YTHDC1ADORA2AADORA3PI4KAPI4K2B | |
| SCHEMBL24196376 | 0.63 | ADORA2A (0.65) | YTHDC1ADORA2AADORA3PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011171-A1 | NOVEL COMPOUNDS AND METHODS FOR INCREASING KLOTHO GENE EXPRESSION | KLOTHO THERAPEUTICS, INC. (US) | 2022-01-13 | — | — | WO | disclosed |