Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 12/20 | 0.46 |
| ▸ | TAB1 | Q15750 | 12/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348310 | 0.84 | MAP3K7 (0.44) | MAP3K7TAB1TDO2GSK3BCCNC | |
| SCHEMBL16945246 | 0.83 | MAP3K7 (0.42) | MAP3K7TAB1TDO2GSK3BCLK1 | |
| SCHEMBL18238538 | 0.83 | MAP3K7 (0.42) | MAP3K7TAB1TDO2GSK3BCLK1 | |
| SCHEMBL18238563 | 0.82 | MAP3K7 (0.44) | MAP3K7TAB1GSK3B | |
| SCHEMBL16945239 | 0.82 | MAP3K7 (0.44) | MAP3K7TAB1GSK3B | |
| SCHEMBL18238269 | 0.82 | MAP3K7 (0.46) | MAP3K7TAB1TDO2GSK3BCLK1 | |
| SCHEMBL16932992 | 0.82 | AXL (0.44) | MAP3K7TAB1TDO2GSK3BGSK3A | |
| SCHEMBL16932991 | 0.82 | AXL (0.44) | MAP3K7TAB1TDO2GSK3BGSK3A | |
| SCHEMBL16945189 | 0.82 | MAP3K7 (0.46) | MAP3K7TAB1TDO2GSK3BCLK1 | |
| SCHEMBL18238111 | 0.82 | KIT (0.46) | MAP3K7TAB1TDO2CLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180434-A1 | PB2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |
| WO-2022007966-A1 | PB2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川海思科制药有限公司 | 2022-01-13 | — | — | WO | disclosed |