Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 12/20 | 0.44 |
| ▸ | TAB1 | Q15750 | 12/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 6/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16945239 | 1.00 | MAP3K7 (0.44) | MAP3K7TAB1KMT2AGSK3BAXL | |
| SCHEMBL18250590 | 0.86 | MAP3K7 (0.44) | MAP3K7TAB1KMT2AGSK3BAXL | |
| SCHEMBL4348310 | 0.83 | MAP3K7 (0.44) | MAP3K7TAB1GSK3BAXL | |
| SCHEMBL24764929 | 0.82 | KMT2A (0.54) | KMT2AGSK3BAXL | |
| SCHEMBL24197757 | 0.82 | MAP3K7 (0.46) | MAP3K7TAB1GSK3B | |
| SCHEMBL16945143 | 0.80 | MAP3K7 (0.53) | MAP3K7TAB1GSK3BAXL | |
| SCHEMBL18238627 | 0.80 | MAP3K7 (0.53) | MAP3K7TAB1GSK3BAXL | |
| SCHEMBL18238269 | 0.78 | MAP3K7 (0.46) | MAP3K7TAB1GSK3B | |
| SCHEMBL16945189 | 0.78 | MAP3K7 (0.46) | MAP3K7TAB1GSK3B | |
| SCHEMBL4346952 | 0.78 | MAP3K7 (0.43) | MAP3K7TAB1GSK3BAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499551-B2 | Substituted pyrrolo[2,3-b]pyridines for treating cancer or inflammatory diseases | CONFLUENCE LIFE SCIENCES, INC. (US) | 2016-11-22 | — | — | US | disclosed |