Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198772 | 0.83 | TAS1R3 (0.38) | ALDH1A1LOXL2LMNA | |
| SCHEMBL24198724 | 0.81 | AR (0.50) | ALDH1A1LMNASMN1; SMN2HTTNPC1 | |
| SCHEMBL24198795 | 0.81 | TAS1R3 (0.38) | ALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL29227517 | 0.75 | DDR1 (0.46) | DDR1VNN1ALDH1A1LOXL2LMNA | |
| SCHEMBL24198695 | 0.75 | DDR1 (0.42) | DDR1ALDH1A1LMNA | |
| Alcohol SCHEMBL28244007 | 0.74 | KDM4C (0.47) | DDR1VNN1ALDH1A1LOXL2LMNA | |
| SCHEMBL16690807 | 0.73 | SMARCA2 (0.49) | DDR1VNN1LOXL2LMNASMN1; SMN2 | |
| SCHEMBL30016958 | 0.73 | SMARCA2 (0.49) | DDR1VNN1LOXL2LMNASMN1; SMN2 | |
| SCHEMBL28019417 | 0.72 | VNN1 (0.58) | DDR1VNN1LOXL2LOXSMARCA2 | |
| SCHEMBL15720401 | 0.71 | SYK (0.54) | DDR1VNN1ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | MONASH UNIVERSITY (AU) | 2022-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | VIP, PNKP, PEPD | DDR1 2252/4885VNN1 205/4885ALDH1A1 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.