Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 3/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198724 | 0.83 | AR (0.50) | CA12CA9ARKDM5AKDM5B | |
| SCHEMBL24198772 | 0.83 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2ARKDM5A | |
| SCHEMBL24198786 | 0.82 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2CA12CA9 | |
| SCHEMBL24198752 | 0.81 | DDR1 (0.43) | SMARCA2SMARCA4ALDH1A1 | |
| SCHEMBL15114397 | 0.78 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2CA12CA9 | |
| SCHEMBL30237286 | 0.75 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2CA12CA9 | |
| SCHEMBL18994707 | 0.72 | HPGD (0.47) | TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL5860112 | 0.72 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2CA12CA9 | |
| SCHEMBL20902727 | 0.70 | ADORA3 (0.42) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL21919758 | 0.70 | CA5A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | MONASH UNIVERSITY (AU) | 2022-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | VIP, PNKP, PEPD | TAS1R3 3926/4885TAS1R1 4287/4885TAS1R2 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.