Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.64 |
| ▸ | CTSL | P07711 | 6/20 | 0.62 |
| ▸ | CTSB | P07858 | 3/20 | 0.62 |
| ▸ | CTSS | P25774 | 3/20 | 0.62 |
| ▸ | CTSV | O60911 | 1/20 | 0.62 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24199737 | 0.91 | CTSK (0.78) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL2155514 | 0.91 | CTSK (0.78) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL22733918 | 0.86 | CTSK (0.83) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL22733917 | 0.86 | CTSK (0.83) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL15894170 | 0.86 | CTSK (0.83) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL2156458 | 0.85 | CTSK (0.69) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL24199833 | 0.83 | CTSB (0.63) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL5742250 | 0.81 | CTSK (0.85) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL2948347 | 0.80 | CTSB (0.60) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL2948349 | 0.80 | CTSB (0.60) | CTSKCTSLCTSBCTSSCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720840-B1 | CATHEPSIN INHIBITORS | ACADEMISCH ZIEKENHUIS LEIDEN (NL) | 2022-01-19 | — | — | EP | disclosed |