Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899417 | 0.90 | TBXAS1 (0.40) | TBXAS1PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL24200170 | 0.89 | TBXAS1 (0.42) | TBXAS1PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL21455427 | 0.85 | TBXAS1 (0.42) | TBXAS1PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL23617253 | 0.83 | TBXAS1 (0.47) | TBXAS1PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL7888801 | 0.83 | TBXAS1 (0.49) | TBXAS1PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL23616962 | 0.81 | TBXAS1 (0.46) | TBXAS1PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL24200130 | 0.79 | TBXAS1 (0.39) | TBXAS1PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL23229153 | 0.79 | TBXAS1 (0.48) | TBXAS1PKMCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL21455682 | 0.79 | TBXAS1 (0.44) | TBXAS1PKMCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL24200196 | 0.78 | TBXAS1 (0.39) | TBXAS1PKMCYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |