Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200319 | 0.88 | MEN1 (0.32) | ALDH1A1CYP1A2CYP2C19L3MBTL1LMNA | |
| SCHEMBL24200130 | 0.81 | TBXAS1 (0.39) | TBXAS1PKMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL21455546 | 0.81 | TBXAS1 (0.40) | TBXAS1PKMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL24199896 | 0.80 | TBXAS1 (0.34) | TBXAS1PKML3MBTL1LMNAGAA | |
| SCHEMBL24200223 | 0.80 | TBXAS1 (0.40) | TBXAS1PKMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL24200170 | 0.79 | TBXAS1 (0.42) | TBXAS1PKMALDH1A1L3MBTL1LMNA | |
| SCHEMBL21455140 | 0.79 | TBXAS1 (0.39) | TBXAS1PKMALDH1A1KDM4ECYP1A2 | |
| SCHEMBL21455682 | 0.79 | TBXAS1 (0.44) | TBXAS1PKML3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL24200089 | 0.78 | TBXAS1 (0.42) | TBXAS1PKMALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL24200210 | 0.78 | MEN1 (0.33) | ALDH1A1CYP1A2CYP2C19L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |