Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455145 | 0.89 | TBXAS1 (0.36) | SMN1; SMN2KDM4EALDH1A1L3MBTL1AKR1C3 | |
| SCHEMBL25894394 | 0.89 | TBXAS1 (0.36) | SMN1; SMN2KDM4EALDH1A1L3MBTL1AKR1C3 | |
| SCHEMBL21562070 | 0.88 | MAOB (0.31) | HPGDMEN1KMT2A | |
| SCHEMBL24555300 | 0.88 | EGFR (0.31) | AKR1C3AKR1C2 | |
| SCHEMBL23241659 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL21455391 | 0.82 | TBXAS1 (0.36) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL25894459 | 0.82 | TBXAS1 (0.36) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL21562075 | 0.81 | MEN1 (0.33) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL21455609 | 0.81 | UCHL1 (0.31) | — | |
| SCHEMBL21455784 | 0.80 | L3MBTL1 (0.41) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |