Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23228992 | 0.90 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTALDH1A1PPARG | |
| SCHEMBL21455751 | 0.87 | ALDH1A1 (0.53) | MAPTALDH1A1PPARGPOLBTDP1 | |
| SCHEMBL30482840 | 0.87 | ALDH1A1 (0.53) | MAPTALDH1A1PPARGPOLBTDP1 | |
| SCHEMBL23229241 | 0.85 | HSD17B10 (0.59) | MTNR1AMTNR1BPOLBCNR1CNR2 | |
| SCHEMBL21455279 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1PPARGPOLBTDP1 | |
| SCHEMBL31053251 | 0.82 | HPGD (0.45) | MAPTALDH1A1POLBTDP1DPP4 | |
| SCHEMBL23617308 | 0.82 | DPP4 (0.48) | MAPTALDH1A1POLBTDP1DPP4 | |
| SCHEMBL24200347 | 0.80 | ALDH1A1 (0.42) | MTNR1AMTNR1BMAPTALDH1A1PPARG | |
| SCHEMBL12093646 | 0.80 | PPARG (0.48) | MAPTALDH1A1PPARGL3MBTL1LMNA | |
| SCHEMBL23656671 | 0.79 | ALDH1A1 (0.41) | MAPTALDH1A1PPARGPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |