Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403976 | 0.86 | ITGB1 (0.55) | ITGB1ITGA4NPC1RAB9AALDH1A1 | |
| SCHEMBL20436314 | 0.81 | ITGB1 (0.37) | PARP14ITGB1ITGA4NPC1RAB9A | |
| SCHEMBL20458582 | 0.81 | CHRM3 (0.35) | ITGB1ITGA4ALDH1A1KDM4EGSK3A | |
| SCHEMBL20436310 | 0.79 | NLRP3 (0.36) | ITGB1ITGA4NPC1RAB9AALDH1A1 | |
| SCHEMBL20436323 | 0.79 | MAPT (0.49) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL20436324 | 0.77 | ALDH1A1 (0.47) | NPC1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL11709551 | 0.76 | MAPT (0.53) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL4401959 | 0.76 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL14960464 | 0.74 | ABCC1 (0.47) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL10030203 | 0.74 | POLB (0.39) | ITGB1ITGA4NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3358346-B1 | ENANTIOMER ANALYSIS METHOD | AJINOMOTO KK (JP) | 2022-01-19 | — | — | EP | disclosed |