Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.34 |
| ▸ | SRC | P12931 | 11/20 | 0.34 |
| ▸ | KDR | P35968 | 9/20 | 0.34 |
| ▸ | FLT1 | P17948 | 8/20 | 0.34 |
| ▸ | ABL1 | P00519 | 7/20 | 0.34 |
| ▸ | SYK | P43405 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200722 | 0.73 | JAK3 (0.50) | — | |
| SCHEMBL24200698 | 0.71 | ALDH1A1 (0.36) | KDR | |
| SCHEMBL22418526 | 0.70 | HTR6 (0.34) | EGFRSRCKDRFLT1ABL1 | |
| SCHEMBL22418528 | 0.70 | HTR6 (0.34) | EGFRSRCKDRFLT1ABL1 | |
| SCHEMBL22418524 | 0.70 | HTR6 (0.34) | EGFRSRCKDRFLT1ABL1 | |
| SCHEMBL24200804 | 0.70 | JAK3 (0.31) | SRC | |
| SCHEMBL28647729 | 0.69 | EGFR (0.36) | EGFRSRCKDRFLT1ABL1 | |
| SCHEMBL28647730 | 0.69 | EGFR (0.36) | EGFRSRCKDRFLT1ABL1 | |
| SCHEMBL22436103 | 0.66 | JAK1 (0.36) | EGFR | |
| SCHEMBL22436102 | 0.66 | HTR6 (0.35) | EGFRSRCKDRFLT1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939979-A1 | JAK KINASE INHIBITOR, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF IN FIELD OF MEDICINE | Shanghai Synergy Pharmaceutical Sciences Co., Ltd (CN) | 2022-01-19 | — | — | EP | disclosed |