Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.35 |
| ▸ | CLK1 | P49759 | 3/20 | 0.35 |
| ▸ | CLK3 | P49761 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.35 |
| ▸ | DYRK4 | Q9NR20 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201201 | 0.73 | LMNA (0.42) | — | |
| SCHEMBL17295436 | 0.68 | FAAH (0.59) | — | |
| SCHEMBL17295434 | 0.68 | FAAH (0.59) | — | |
| SCHEMBL20932989 | 0.62 | CYP2A6 (0.36) | — | |
| SCHEMBL18911976 | 0.62 | MAOB (0.52) | MAOBDYRK3CLK1CLK3DYRK1A | |
| SCHEMBL22420193 | 0.60 | FAAH (0.35) | ESR1 | |
| SCHEMBL20932919 | 0.59 | FAAH (0.50) | DYRK3DYRK1ACLK4DYRK4CLK2 | |
| SCHEMBL20932996 | 0.59 | MEN1 (0.42) | — | |
| SCHEMBL17295633 | 0.59 | FAAH (0.53) | MAOBDYRK3CLK1CLK3DYRK1A | |
| SCHEMBL17295534 | 0.58 | FAAH (0.52) | DYRK3CLK1CLK3DYRK1ADYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-B1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | UNIV BERN (CH) | 2022-01-19 | — | — | EP | disclosed |