Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295436 | 0.80 | FAAH (0.59) | LMNAAURKATDP1FAAHMEN1 | |
| SCHEMBL17295434 | 0.80 | FAAH (0.59) | LMNAAURKATDP1FAAHMEN1 | |
| SCHEMBL24201200 | 0.73 | MAOB (0.37) | — | |
| SCHEMBL17295401 | 0.70 | ALDH1A1 (0.49) | LMNAAURKAPTPN1ACP1FAAH | |
| SCHEMBL17295402 | 0.70 | ALDH1A1 (0.49) | LMNAAURKAPTPN1ACP1FAAH | |
| SCHEMBL17295605 | 0.69 | FAAH (0.55) | LMNAFAAHSMN1; SMN2CA9CA2 | |
| SCHEMBL17295607 | 0.69 | FAAH (0.55) | LMNAFAAHSMN1; SMN2CA9CA2 | |
| SCHEMBL17295633 | 0.68 | FAAH (0.53) | AURKAFAAHCA9ALDH1A1KMT2A | |
| SCHEMBL17295634 | 0.68 | FAAH (0.53) | AURKAFAAHCA9ALDH1A1KMT2A | |
| SCHEMBL17295536 | 0.68 | FAAH (0.52) | FAAHSMN1; SMN2CA9CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-B1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | UNIV BERN (CH) | 2022-01-19 | — | — | EP | disclosed |