Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | HINT1 | P49773 | 1/20 | 0.58 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201476 | 0.89 | DNPH1 (0.65) | DNPH1ADORA3TP53SLC29A1TDP1 | |
| SCHEMBL22458334 | 0.85 | HINT1 (0.56) | DNPH1SLC29A1NT5EADORA2AADORA1 | |
| SCHEMBL14689162 | 0.84 | DNPH1 (0.83) | DNPH1ADORA3TP53SLC29A1TDP1 | |
| SCHEMBL639152 | 0.83 | ADORA3 (0.82) | ADORA3TP53SLC29A1TDP1ADORA2A | |
| SCHEMBL639151 | 0.83 | ADORA3 (0.82) | ADORA3TP53SLC29A1TDP1ADORA2A | |
| SCHEMBL17825910 | 0.83 | ADORA3 (0.82) | ADORA3TP53SLC29A1TDP1ADORA2A | |
| SCHEMBL17824474 | 0.83 | ADORA3 (0.82) | ADORA3TP53SLC29A1TDP1ADORA2A | |
| SCHEMBL30627968 | 0.83 | ADORA3 (0.82) | ADORA3TP53SLC29A1TDP1ADORA2A | |
| SCHEMBL22458245 | 0.83 | ADORA3 (0.65) | DNPH1ADORA3TP53SLC29A1TDP1 | |
| SCHEMBL918592 | 0.82 | DNPH1 (0.74) | DNPH1ADORA3TP53SLC29A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939988-A1 | PHARMACEUTICAL COMPOSITION COMPRISING NOVEL AZOLOPYRIMIDINE HETEROCYCLIC COMPOUND AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2022-01-19 | — | — | EP | disclosed |