Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 14/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201251 | 1.00 | EPHX2 (0.43) | EPHX2ALDH1A1PTP4A3CYP3A4CYP2C19 | |
| SCHEMBL24201256 | 0.98 | EPHX2 (0.41) | EPHX2ALDH1A1PTP4A3CYP3A4CYP2C19 | |
| SCHEMBL24201248 | 0.88 | EPHX2 (0.45) | EPHX2ALDH1A1PTP4A3SMN1; SMN2 | |
| SCHEMBL24201339 | 0.88 | EPHX2 (0.45) | EPHX2ALDH1A1PTP4A3SMN1; SMN2 | |
| SCHEMBL24201255 | 0.80 | EPHX2 (0.60) | EPHX2ALDH1A1PTP4A3CYP3A4CYP2C19 | |
| SCHEMBL24201206 | 0.79 | ALDH1A1 (0.45) | EPHX2ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL24201335 | 0.79 | ALDH1A1 (0.59) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL17457697 | 0.78 | ALDH1A1 (0.60) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL24201130 | 0.72 | EPHX2 (0.33) | EPHX2OPRK1 | |
| SCHEMBL24201269 | 0.72 | EPHX2 (0.33) | EPHX2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3618833-B1 | TRIPARTITE ANDROGEN RECEPTOR ELIMINATORS, METHODS AND USES THEREOF | SPG THERAPEUTICS INC (US) | 2022-01-19 | — | — | EP | disclosed |