Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 2/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24202016 | 0.93 | MKNK1 (0.36) | KMT2AMEN1NPSR1EIF4EMKNK1 | |
| SCHEMBL23761212 | 0.92 | MKNK1 (0.45) | NPSR1NPC1EIF4EMKNK1MKNK2 | |
| SCHEMBL24201711 | 0.88 | MKNK1 (0.44) | KMT2AMEN1EIF4EMKNK1MKNK2 | |
| SCHEMBL23761391 | 0.85 | MKNK1 (0.45) | KMT2AMEN1EIF4EMKNK1MKNK2 | |
| SCHEMBL24202077 | 0.83 | MKNK1 (0.37) | KMT2AMEN1EIF4EMKNK1MKNK2 | |
| SCHEMBL24202175 | 0.83 | MKNK1 (0.45) | NPSR1EIF4EMKNK1MKNK2NOTUM | |
| SCHEMBL23761356 | 0.83 | MKNK1 (0.33) | NPSR1EIF4EMKNK1MKNK2NOTUM | |
| SCHEMBL23761657 | 0.81 | MKNK1 (0.49) | EIF4EMKNK1MKNK2NOTUMSIRT2 | |
| SCHEMBL23761530 | 0.79 | NOTUM (0.40) | NPSR1NPC1EIF4EMKNK1MKNK2 | |
| SCHEMBL24202017 | 0.79 | NOTUM (0.41) | NPSR1NPC1EIF4EMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939981-A1 | FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS | LifeArc (GB) | 2022-01-19 | — | — | EP | disclosed |