Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294864 | 0.84 | OPRM1 (0.45) | MEN1KMT2APOLBOPRM1OPRK1 | |
| SCHEMBL25890239 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2APOLBOPRM1OPRK1 | |
| SCHEMBL5539734 | 0.80 | MEN1 (0.56) | MEN1KMT2APOLBPDE4APDE4B | |
| SCHEMBL4602881 | 0.79 | MPI (0.43) | MEN1KMT2APOLBOPRM1OPRK1 | |
| SCHEMBL5539731 | 0.79 | MEN1 (0.50) | MEN1KMT2APOLBPDE4APDE4B | |
| SCHEMBL31251202 | 0.79 | MEN1 (0.50) | MEN1KMT2APOLBPDE4APDE4B | |
| SCHEMBL29267762 | 0.79 | MEN1 (0.58) | MEN1KMT2APOLBPDE4APDE4B | |
| SCHEMBL9028558 | 0.79 | MEN1 (0.50) | MEN1KMT2APOLBPDE4APDE4B | |
| SCHEMBL10381827 | 0.79 | PKM (0.51) | MEN1KMT2APOLBPDE4APDE4B | |
| SCHEMBL13993447 | 0.79 | MEN1 (0.50) | MEN1KMT2APOLBPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939981-A1 | FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS | LifeArc (GB) | 2022-01-19 | — | — | EP | disclosed |
| CN-108752258-A | Nickel is catalyzed Synthesis of Indole ketones derivant | 南开大学 | 2018-11-06 | — | — | CN | disclosed |