Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.68 |
| ▸ | ADH1C | P00326 | 1/20 | 0.68 |
| ▸ | ADH1A | P07327 | 1/20 | 0.68 |
| ▸ | ADH4 | P08319 | 1/20 | 0.68 |
| ▸ | ADH7 | P40394 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030276 | 0.90 | ADH1B (0.61) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL304641 | 0.84 | — | — | |
| SCHEMBL303776 | 0.82 | ADH1A (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL5651614 | 0.82 | ADH1A (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL8606031 | 0.82 | ADH1A (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL8952019 | 0.82 | ADH1A (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1608989 | 0.82 | — | — | |
| SCHEMBL3469190 | 0.79 | ADH1B (0.59) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL2385282 | 0.79 | ADH1B (0.59) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL3715748 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939981-A1 | FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS | LifeArc (GB) | 2022-01-19 | — | — | EP | disclosed |