Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.87 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.87 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.87 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.87 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.87 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13743155 | 1.00 | F2 (0.87) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19705583 | 0.86 | PLCD1 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL18779801 | 0.84 | TDP1 (0.78) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24590149 | 0.84 | F2 (0.66) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL20006677 | 0.84 | TDP1 (0.71) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL22493325 | 0.84 | HLCS (0.71) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15870672 | 0.84 | HLCS (0.71) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL2632289 | 0.84 | TDP1 (0.71) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL17881931 | 0.84 | TDP1 (0.71) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12320610 | 0.84 | HLCS (0.71) | F2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220018849-A1 | SERINE HYDROLASE PROFILING ASSAY IN BIOTHERAPEUTICS | MERCK SHARP & DOHME LLC | 2022-01-20 | — | — | US | disclosed |