Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841375 | 0.84 | MEN1 (0.37) | TSHRMEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL22335 | 0.84 | MEN1 (0.37) | TSHRMEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL4168927 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1AKR1C3CYP2C9FBP1 | |
| SCHEMBL4160807 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1AKR1C3CYP2C9FBP1 | |
| SCHEMBL23444 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1AKR1C3CYP2C9FBP1 | |
| SCHEMBL23069335 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1AKR1C3CYP2C9FBP1 | |
| SCHEMBL27841652 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1AKR1C3CYP2C9FBP1 | |
| SCHEMBL27778800 | 0.81 | FBP1 (0.32) | TSHRMEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL2418975 | 0.81 | ALDH1A1 (0.41) | TSHRMEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL23364 | 0.80 | MEN1 (0.47) | TSHRMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604992-B2 | Compounds of dibenzylidene sorbitol ester type, process of preparation, use, compositions comprising them and cosmetic treatment method | L'OREAL (FR) | 2017-03-28 | — | — | US | disclosed |
| US-20130039862-A1 | COMPOUNDS OF DIBENZYLIDENE SORBITOL ESTER TYPE, PROCESS OF PREPARATION, USE, COMPOSITIONS COMPRISING THEM AND COSMETIC TREATMENT METHOD | L'OREAL (FR) | 2013-02-14 | — | — | US | disclosed |
| EP-2542556-A1 | COMPOUNDS OF DIBENZYLIDENE SORBITOL ESTER TYPE, PROCESS OF PREPARATION, USE, COMPOSITIONS COMPRISING THEM AND COSMETIC TREATMENT METHOD | L'Oréal (FR) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011107403-A1 | COMPOUNDS OF DIBENZYLIDENE SORBITOL ESTER TYPE, PROCESS OF PREPARATION, USE, COMPOSITIONS COMPRISING THEM AND COSMETIC TREATMENT METHOD | L'OREAL (FR) | 2011-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130039862-A1 | COMPOUNDS OF DIBENZYLIDENE SORBITOL ESTER TYPE, PROCESS OF PREPARATION, USE, COMPOSITIONS COMPRISING THEM AND COSMETIC TREATMENT METHOD | C1R, SORD, C1S | TSHR 1195/4885MEN1 1965/4885KMT2A 2686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.