SCHEMBL2420372

SCHEMBL2420372

CCOC(=O)Cc1cccc(Br)c1Br

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.47
▸ NLRP3 Q96P20 2/20 0.44
▸ CYP4F2 P78329 2/20 0.44
▸ CYP4A11 Q02928 2/20 0.44
▸ GABRA1 P14867 1/20 0.42
▸ GABRB2 P47870 1/20 0.42
▸ GAA P10253 2/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ TBXAS1 P24557 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA7 P43166 1/20 0.40
▸ CA9 Q16790 1/20 0.40
▸ CA14 Q9ULX7 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2417816 0.87 ALDH1A1 (0.41) PKMGABRA1GABRB2KMT2ATDP1
SCHEMBL6212971 0.87 NLRP3 (0.48) PKMNLRP3CYP4F2CYP4A11GABRA1
SCHEMBL852520 0.86 PKM (0.53) PKMNLRP3CYP4F2CYP4A11TSHR
SCHEMBL29511550 0.86 PKM (0.53) PKMNLRP3CYP4F2CYP4A11TSHR
SCHEMBL23218990 0.85 PKM (0.46) PKMNLRP3CYP4F2CYP4A11GABRA1
SCHEMBL30950183 0.85 PKM (0.46) PKMNLRP3CYP4F2CYP4A11GABRA1
SCHEMBL2420567 0.84 TSHR (0.44) KMT2ATDP1TSHRALDH1A1L3MBTL1
SCHEMBL671835 0.84 PKM (0.44) PKMNLRP3CYP4F2CYP4A11GAA
SCHEMBL17670986 0.84 PKM (0.48) PKMNLRP3CYP4F2CYP4A11GABRA1
SCHEMBL27508381 0.84 PKM (0.44) PKMNLRP3CYP4F2CYP4A11GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278404-B2 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 — — US disclosed
US-20110224390-A1 PROCESS FOR PRODUCING COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-15 — — US disclosed
US-7262258-B2 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-28 — — US disclosed
US-20070088139-A1 PROCESS FOR PRODUCING COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED 2007-04-19 — — US disclosed
US-20050014914-A1 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-01-20 — — US disclosed
US-5728911-A CATALYTIC SOLUTION COPOLYMERIZATION OF ETHYLENE WITH POLYUNSATURATED MONOMER DSM COPOLYMER, INC. (US) 1998-03-17 — — US disclosed
EP-0705284-B1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1997-07-09 — — EP disclosed
EP-0705284-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1996-04-10 — — EP disclosed
WO-1995000564-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM N.V. (NL) 1995-01-05 — — WO disclosed
EP-0044119-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE STAMICARBON B.V. (NL) 1985-05-29 — — EP disclosed
US-4435552-A COORDINATION CATALYST CONTAINING HALOACYL COMPOUND STAMICARBON B.V. (NL) 1984-03-06 — — US disclosed
EP-0044119-A2 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-20 — — EP disclosed
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