Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854177 | 0.91 | CA1 (0.44) | TDP1ALDH1A1SMN1; SMN2MAPTPKM | |
| SCHEMBL2648403 | 0.83 | CA12 (0.59) | TDP1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL22115709 | 0.83 | TSHR (0.52) | TDP1ALDH1A1CES2CES1SMN1; SMN2 | |
| SCHEMBL28620726 | 0.82 | CA1 (0.63) | TDP1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL15090414 | 0.81 | CA1 (0.38) | TDP1ALDH1A1SMN1; SMN2MAPTPKM | |
| SCHEMBL229327 | 0.80 | TSHR (0.58) | TDP1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL2419117 | 0.79 | ALDH1A1 (0.55) | TDP1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL14354319 | 0.79 | TDP1 (0.55) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL8778149 | 0.79 | TDP1 (0.55) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL27469371 | 0.78 | TSHR (0.56) | TDP1ALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108978226-A | A kind of preparation of polyurethane-modified polyacrylate class water repellent and application method | 江南大学 | 2018-12-11 | — | — | CN | claimed |
| US-20090018234-A1 | DENTAL CEMENT | GC CORPORATION (JP) | 2009-01-15 | — | — | US | claimed |
| WO-2021106683-A1 | PHOTOSENSITIVE INK COMPOSITION, CURED PRODUCT, DISPLAY PANEL, AND METHOD FOR PRODUCING CURED PRODUCT | 東京応化工業株式会社 | 2021-06-03 | — | — | WO | disclosed |
| CN-109641395-A | The manufacturing method of ink-jet 3D printer photo-curable backing material composition, ink-jet 3D printer ink, ink-jet 3D printer print cartridge, the manufacturing method of backing material and light chisel object | 株式会社日本触媒 | 2019-04-16 | — | — | CN | disclosed |
| CN-108978226-A | A kind of preparation of polyurethane-modified polyacrylate class water repellent and application method | 江南大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-107057252-A | A kind of sunglasses eyeglass and preparation method thereof | 浙江工贸职业技术学院 | 2017-08-18 | — | — | CN | disclosed |
| EP-2600874-B1 | PYRIMIDINE COMPOUNDS THAT INHIBIT ANAPLASTIC LYMPHOMA KINASE | AMGEN INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8716281-B2 | Pyrimidine compounds that inhibit anaplastic lymphoma kinase | AMGEN INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20130158019-A1 | PYRIMIDINE COMPOUNDS THAT INHIBIT ANAPLASTIC LYMPHOMA KINASE | AMGEN INC. (US) | 2013-06-20 | — | — | US | disclosed |
| EP-2011468-B1 | Dental Cement | G C DENTAL IND CORP (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-20090018234-A1 | DENTAL CEMENT | GC CORPORATION (JP) | 2009-01-15 | — | — | US | disclosed |
| EP-2011468-A1 | Dental Cement | GC Corporation (JP) | 2009-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158019-A1 | PYRIMIDINE COMPOUNDS THAT INHIBIT ANAPLASTIC LYMPHOMA KINASE | DCK, DTYMK, TYMS | TDP1 333/4885ALDH1A1 725/4885LMNA 2820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.