SCHEMBL22115709

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4854177	0.91	CA1 (0.44)	TSHRALDH1A1CA1CA2SMN1; SMN2
	SCHEMBL229327	0.84	TSHR (0.58)	TSHRTP53ALDH1A1SMN1; SMN2MAPT
	SCHEMBL27469371	0.83	TSHR (0.56)	TSHRTP53ALDH1A1SMN1; SMN2MAPT
	SCHEMBL2420458	0.83	TDP1 (0.59)	ALDH1A1SMN1; SMN2SRD5A2MAPTKMT2A
	SCHEMBL2648403	0.83	CA12 (0.59)	TSHRALDH1A1CA1CA2SMN1; SMN2
	SCHEMBL15090414	0.81	CA1 (0.38)	TSHRALDH1A1CA1CA2SMN1; SMN2
	SCHEMBL28809439	0.80	HSD17B10 (0.48)	ALDH1A1CA1CA2MAPTCA12
	SCHEMBL2419117	0.79	ALDH1A1 (0.55)	TSHRALDH1A1CA1CA2SMN1; SMN2
	SCHEMBL6646577	0.79	TSHR (0.43)	TSHRTP53ALDH1A1CA1CA2
	Terephthalic Acid SCHEMBL9407876	0.78	TSHR (0.75)	TSHRTP53ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.