Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802286 | 0.88 | ITGB3 (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL24204530 | 0.86 | KMT2A (0.49) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL24204567 | 0.82 | MEN1 (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL24206641 | 0.78 | ACACB (0.43) | MEN1KMT2AALDH1A1HRH3GNAI3 | |
| SCHEMBL24803097 | 0.77 | L3MBTL1 (0.49) | MEN1KMT2AMAPTHRH3GNAI3 | |
| SCHEMBL26067161 | 0.77 | ITGB3 (0.54) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL19313001 | 0.74 | KDM4E (0.41) | MEN1KMT2AALDH1A1KDM4EHRH3 | |
| SCHEMBL24802116 | 0.74 | MEN1 (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL25955527 | 0.74 | KMT2A (0.57) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL26042822 | 0.71 | KMT2A (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022012623-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-01-20 | — | — | WO | disclosed |