Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24803097 | 0.92 | L3MBTL1 (0.49) | ACACBACACAL3MBTL1NPC1GNAI3 | |
| SCHEMBL24204794 | 0.85 | GNAI3 (0.51) | ACACBACACAL3MBTL1GNAI3GNAI1 | |
| SCHEMBL24204480 | 0.84 | GNAI3 (0.51) | ACACBACACAGNAI3GNAI1GNAO1 | |
| SCHEMBL8229259 | 0.83 | ALDH1A1 (0.56) | HRH3KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL19157192 | 0.82 | L3MBTL1 (0.53) | L3MBTL1NPC1GNAI3GNAI1GNAO1 | |
| SCHEMBL14614943 | 0.81 | MEN1 (0.59) | L3MBTL1NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11490502 | 0.81 | GNAI3 (0.51) | ACACBACACAGNAI3GNAI1GNAO1 | |
| SCHEMBL19313001 | 0.80 | KDM4E (0.41) | L3MBTL1HRH3KMT2AMEN1ALDH1A1 | |
| SCHEMBL24584949 | 0.79 | MEN1 (0.43) | ACACBACACANPC1GNAI3GNAI1 | |
| SCHEMBL26005384 | 0.79 | GNAI3 (0.60) | ACACBACACAL3MBTL1NPC1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022012622-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-01-20 | — | — | WO | disclosed |