Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514064 | 0.89 | POLB (0.53) | ALDH1A1POLBMAPTLMNANPSR1 | |
| SCHEMBL11213755 | 0.88 | MAPT (0.51) | ALDH1A1POLBMAPTLMNANPSR1 | |
| SCHEMBL11040659 | 0.86 | LMNA (0.50) | POLBMAPTLMNANPSR1KMT2A | |
| SCHEMBL244204 | 0.84 | HTT (0.55) | ALDH1A1POLBMAPTLMNANPSR1 | |
| SCHEMBL4407029 | 0.84 | MAPT (0.48) | ALDH1A1POLBMAPTLMNANPSR1 | |
| SCHEMBL8356481 | 0.84 | MAPT (0.46) | ALDH1A1POLBMAPTLMNANPSR1 | |
| SCHEMBL11234897 | 0.83 | KMT2A (0.51) | ALDH1A1POLBMAPTLMNANPSR1 | |
| SCHEMBL11139586 | 0.83 | FFAR1 (0.47) | ALDH1A1POLBMAPTLMNANPSR1 | |
| SCHEMBL28544663 | 0.81 | POLB (0.54) | ALDH1A1POLBMAPTLMNANPSR1 | |
| SCHEMBL12921171 | 0.80 | HTT (0.50) | ALDH1A1POLBMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3834017-B1 | HIGH WATER CONTENT OPHTHALMIC DEVICES | BAUSCH & LOMB (US) | 2023-05-10 | — | — | EP | claimed |
| EP-2222736-B1 | HIGH WATER CONTENT SILICONE HYDROGELS | BAUSCH & LOMB (US) | 2011-09-21 | — | — | EP | claimed |