SCHEMBL244204

SCHEMBL244204

C=C(C)C(=O)CC(O)COc1ccc(C(C)(C)c2ccc(OCC(O)CC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.55
HIF1A Q16665 1/20 0.55
AR P10275 2/20 0.53
MAPT P10636 5/20 0.48
POLB P06746 2/20 0.48
LMNA P02545 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 2/20 0.46
KDM4E B2RXH2 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.41
MITF O75030 1/20 0.41
MAPK1 P28482 1/20 0.41
GAA P10253 1/20 0.40
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12921171 0.95 HTT (0.50) HTTHIF1AARMAPTPOLB
SCHEMBL13796233 0.92 HTT (0.47) HTTHIF1AARMAPTPOLB
SCHEMBL7514064 0.85 POLB (0.53) MAPTPOLBLMNANPSR1KMT2A
SCHEMBL11213755 0.84 MAPT (0.51) HTTMAPTPOLBLMNANPSR1
SCHEMBL2420628 0.84 ALDH1A1 (0.52) HTTMAPTPOLBLMNANPSR1
SCHEMBL21675934 0.84 HTT (0.47) HTTHIF1AARMAPTPOLB
SCHEMBL11040659 0.82 LMNA (0.50) MAPTPOLBLMNANPSR1KMT2A
SCHEMBL13497097 0.82 HTT (0.42) HTTHIF1AARMAPTPOLB
SCHEMBL22020008 0.82 HTT (0.53) HTTHIF1AARMAPTPOLB
SCHEMBL20610370 0.82 HTT (0.53) HTTHIF1AARMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3906006-B1 FILLERS FOR DENTAL RESTORATIVE MATERIALS KERR CORP (US) 2025-09-17 EP claimed
EP-3906006-A1 FILLERS FOR DENTAL RESTORATIVE MATERIALS Kerr Corporation (US) 2021-11-10 EP claimed
US-10898415-B2 Fillers for dental restorative materials KERR CORPORATION (US) 2021-01-26 US claimed
WO-2020142098-A1 FILLERS FOR DENTAL RESTORATIVE MATERIALS KERR CORPORATION (US) 2020-07-09 WO claimed
US-20200206090-A1 FILLERS FOR DENTAL RESTORATIVE MATERIALS KERR CORPORATION 2020-07-02 US claimed
EP-1693046-B1 Acid tolerant dental composition KERR CORP (US) 2015-07-01 EP claimed
US-9028254-B2 Dental prosthetics comprising curable acrylate polymer compositions and methods of their use SCIENTIFIC PHARMACEUTICALS, INC. (US) 2015-05-12 US claimed
US-20130302513-A1 DENTAL PROSTHETICS COMPRISING CURABLE ACRYLATE POLYMER COMPOSITIONS AND METHODS OF THEIR USE SCIENT PHARMACEUTICALS INC (US) 2013-11-14 US claimed
WO-2013057519-A1 DENTAL ADHESIVE SYSTEMS KING'S COLLEGE LONDON (GB) 2013-04-25 WO claimed
US-20090239969-A1 DENTAL PROSTHETICS COMPRISING CURABLE ACRYLATE POLYMER COMPOSITIONS AND METHODS OF THEIR USE SCIENTIFIC PHARMACEUTICALS, INC (US) 2009-09-24 US claimed
US-4871534-A METHACRYLATE BINDER, METHACRYLATE POLYMER, PEROXIDE INITIATOR REM SYSTEMS, INC. (US) 1989-10-03 US claimed
US-4490115-A Dental material comprising adducts of 3-methacroyl-2-hydroxypropyl esters with diisocyanates SCIENTIFIC PHARMACEUTICAL, INC. (US) 1984-12-25 US claimed
US-4406625-A Adducts of 1,4-bis[(3-Methacroyl-2-hydroxypropoxy)methyl]cyclohexane and derivatives thereof with isocyanates SCIENTIFIC PHARMACEUTICALS, INC. (US) 1983-09-27 US claimed
US-4380432-A METHACRYLATE, CONJUGATED DIENE ELASTOMER SCIENTIFIC PHARMACEUTICALS (US) 1983-04-19 US claimed
US-4379695-A SEALERS; BINDERS; ADHESIVES; CEMENTS; HIGH STRENGTH; CURING; IN SITU ADDITION POLYMERIZATION SCIENTIFIC PHARMACEUTICALS, INC. (US) 1983-04-12 US claimed
US-4340529-A CURABLE ACRYLATE PRIMER LEE PHARMACEUTICALS, INC. (US) 1982-07-20 US claimed
US-4304893-A CURABLE DENTAL MATERIALS SCIENTIFIC PHARMACEUTICALS, INC. (US) 1981-12-08 US claimed
US-4260701-A Formulation for self-curing artificial fingernails containing methoxyethyl methacrylate LEE PHARMACEUTICALS (US) 1981-04-07 US claimed
US-4221698-A FILLER, SELF-CURING ADDITION COPOLYMER LEE PHARMACEUTICALS (US) 1980-09-09 US claimed
US-4150485-A POLYFUNCTIONAL ACRYLIC ESTER MONOMER, FLUORESCENT METAL OXIDE FILLER, ULTRAVIOLET ABSORBER KIDD PATRICK D 1979-04-24 US claimed