SCHEMBL2420664

SCHEMBL2420664

N#CN(C(=N)NCl)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
USP2 O75604 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4259665 0.75 KMT2A (0.40) ALDH1A1
SCHEMBL8082788 0.74
SCHEMBL9844273 0.73 NPSR1 (0.35) ALDH1A1
SCHEMBL4582110 0.72 SIGMAR1 (0.36) ALDH1A1
SCHEMBL27328209 0.70 IDO1 (0.36) ALDH1A1USP2HSD17B10
SCHEMBL2420665 0.70 POLB (0.36) ALDH1A1
SCHEMBL10873563 0.68 NPSR1 (0.35) ALDH1A1USP2HSD17B10
SCHEMBL7758208 0.67 MTNR1A (0.36) ALDH1A1USP2HSD17B10
SCHEMBL7426969 0.67 ALDH1A1 (0.54) ALDH1A1HSD17B10
SCHEMBL437417 0.67 NPSR1 (0.41) ALDH1A1USP2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150528-A2 PROCESS FOR PREPARATION OF PROGUANIL HYDROCHLORIDE USV Limited (IN) 2010-02-10 EP claimed
WO-2009113092-A2 PROCESS FOR PREPARATION OF PROGUANIL HYDROCHLORIDE USV LIMITED (IN) 2009-09-17 WO claimed
EP-3534866-A1 DENTAL RETRACTION COMPOSITION WITH GUANIDINYL-CONTAINING POLYMER 3M Innovative Properties Company (US) 2019-09-11 EP disclosed
EP-2542889-A1 LIGAND GUANIDINYL FUNCTIONALIZED POLYMERS 3M Innovative Properties Company (US) 2013-01-09 EP disclosed
WO-2011109151-A1 LIGAND GUANIDINYL FUNCTIONALIZED POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-09-09 WO disclosed
EP-2150528-A2 PROCESS FOR PREPARATION OF PROGUANIL HYDROCHLORIDE USV Limited (IN) 2010-02-10 EP disclosed
WO-2009113092-A2 PROCESS FOR PREPARATION OF PROGUANIL HYDROCHLORIDE USV LIMITED (IN) 2009-09-17 WO disclosed