Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.79 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenbendazole SCHEMBL8469702 | 0.89 | LMNA (1.00) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| Fenbendazole SCHEMBL30384658 | 0.89 | LMNA (1.00) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL11809370 | 0.86 | LMNA (0.63) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL11359812 | 0.86 | LMNA (0.77) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| Fenbendazole SCHEMBL31076495 | 0.85 | LMNA (0.85) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL7258034 | 0.83 | LMNA (0.83) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL6393355 | 0.81 | LMNA (0.53) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL24209313 | 0.81 | ABL1 (0.79) | LMNACYP1A2SMN1; SMN2HPGDMAPK1 | |
| Lobendazole SCHEMBL205437 | 0.81 | LMNA (0.64) | LMNAMEN1KMT2ASMN1; SMN2MAPK1 | |
| Lobendazole SCHEMBL29682294 | 0.81 | LMNA (0.64) | LMNAMEN1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017471-A1 | FUNCTIONALITY INDEPENDENT LABELING OF ORGANIC COMPOUNDS | UNIV SHANGHAI TECHNOLOGY (CN) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017471-A1 | FUNCTIONALITY INDEPENDENT LABELING OF ORGANIC COMPOUNDS | PAICS, PFAS, OTC | LMNA 1245/4885CYP1A2 339/4885MEN1 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.