Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18088394 | 0.84 | RAB9A (0.60) | NPC1HDAC6RAB9ACXCR4HDAC3 | |
| SCHEMBL13792281 | 0.80 | RAB9A (0.56) | NPC1HDAC6RAB9ACXCR4HDAC3 | |
| SCHEMBL18313460 | 0.76 | NPC1 (0.46) | NPC1HDAC6RAB9AESRRA | |
| SCHEMBL12049796 | 0.76 | ESRRA (0.50) | NPC1HDAC6RAB9ACXCR4HDAC3 | |
| SCHEMBL22917361 | 0.76 | CXCR4 (0.56) | NPC1HDAC6RAB9ACXCR4HDAC3 | |
| SCHEMBL1565304 | 0.74 | PRMT5 (0.73) | NPC1HDAC6RAB9AHDAC3HDAC4 | |
| SCHEMBL29336471 | 0.74 | HTT (0.62) | NPC1HDAC6RAB9ACXCR4HDAC3 | |
| SCHEMBL22919775 | 0.73 | HDAC6 (0.59) | NPC1HDAC6RAB9AHDAC3HDAC4 | |
| SCHEMBL16663613 | 0.73 | HDAC6 (0.59) | NPC1HDAC6RAB9AHDAC3HDAC4 | |
| SCHEMBL15587410 | 0.73 | CXCR4 (0.65) | NPC1CXCR4PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017454-A1 | OLIGO-BENZAMIDE ANALOGS AND THEIR USE IN CANCER TREATMENT | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017454-A1 | OLIGO-BENZAMIDE ANALOGS AND THEIR USE IN CANCER TREATMENT | OGFR, OTC, HDAC6 | NPC1 2163/4885HDAC6 3/4885RAB9A 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.