Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310255 | 0.84 | ACACB (0.57) | PRSS1PRSS2PRSS3ACACBTAS1R3 | |
| SCHEMBL24211854 | 0.75 | F10 (0.50) | PRSS1PRSS2PRSS3NPC1MAPT | |
| SCHEMBL4100874 | 0.74 | PRSS1 (0.56) | PRSS1PRSS2PRSS3NPC1RAB9A | |
| SCHEMBL24212178 | 0.74 | KMT2A (0.61) | MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2910125 | 0.73 | NQO1 (0.56) | ACACBTAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL9193560 | 0.72 | NOS1 (0.68) | PRSS1PRSS2PRSS3NPC1MAPT | |
| SCHEMBL28616323 | 0.72 | NQO1 (0.74) | ACACBSMN1; SMN2LMNAPARP10NQO1 | |
| SCHEMBL2572011 | 0.72 | PRSS1 (0.61) | PRSS1PRSS2PRSS3SMN1; SMN2LMNA | |
| SCHEMBL1542164 | 0.71 | ST14 (0.45) | PRSS1PRSS2PRSS3ACACBNPC1 | |
| SCHEMBL27793869 | 0.71 | LTA4H (0.70) | LMNAALDH1A1NQO1SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220015367-A1 | SELF-ASSEMBLED ACTIVE AGENTS | METHODS PRODUCTS PBC | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220015367-A1 | SELF-ASSEMBLED ACTIVE AGENTS | PCNA, POLM, MUS81 | PRSS1 1875/4885PRSS2 1708/4885PRSS3 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.