Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24212569 | 0.84 | RAF1 (0.39) | RAF1MAPK14MAPTTSHRKMT2A | |
| SCHEMBL161668 | 0.81 | RAF1 (0.56) | RAF1MAPK14MAPTMAPK13MAPK12 | |
| SCHEMBL24212638 | 0.79 | MAPT (0.44) | RAF1MAPK14MAPTTSHRKMT2A | |
| SCHEMBL29360602 | 0.77 | CFTR (0.39) | MAPTTSHRKMT2AHSD17B10NPC1 | |
| SCHEMBL21152503 | 0.74 | MAPT (0.44) | MAPTTSHRKMT2AHSD17B10NPC1 | |
| SCHEMBL2027674 | 0.73 | MAPT (0.47) | MAPTTSHRKMT2AHSD17B10NPC1 | |
| SCHEMBL29358940 | 0.73 | SOS1 (0.40) | MAPTTSHRKMT2AHSD17B10NPC1 | |
| SCHEMBL2730725 | 0.70 | MAPT (0.44) | MAPTTSHRKMT2AHSD17B10NPC1 | |
| SCHEMBL13545971 | 0.70 | MAPT (0.44) | MAPTTSHRKMT2AHSD17B10NPC1 | |
| SCHEMBL12272115 | 0.70 | MAPT (0.57) | MAPTTSHRKMT2AHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022013417-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-01-20 | — | — | WO | disclosed |